HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: EMSY (Q7Z589)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1322
+	Hs
		1056847 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		1056919 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		918364 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		707631 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		1087210 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		SRCAP_HUMAN (588-1312): 6.01e-16: 86: 9.66
+	Hs
		918462 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		SRCAP_HUMAN (588-1312): 6.01e-16: 86: 9.66
+	Hs
		918628 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		MINT_HUMAN (72-1304): 8.31e-15: 82.4: 10.57
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		617962 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		1087299 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		1264778 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		883041 H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		918533 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KMT2C_HUMAN (136-1005): 1.04e-12: 75.6: 6.91
+	Hs
		152598 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Hs
		1087188 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		1087225 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11
+	Hs
		918477 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11
+	Hs
		707655 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		1224362 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		AGRG4_HUMAN (82-754): 8.58e-10: 65.9: 11.00