HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: IWS1 (Q96ST2)
Protein IWS1 homolog (IWS1-like protein)
Gene: IWS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 819
+	Hs
		707767 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		MDN1_HUMAN (1-719): 4.71e-126: 420: 14.79
+	Hs
		918625 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		IWS1_HUMAN (1-819): 1.85e-132: 416: 100.00
+	Hs
		241617 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		IWS1_HUMAN (1-819): 1.85e-132: 416: 100.00
+	Hs
		1282949 H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04		IWS1_HUMAN (1-819): 1.85e-132: 416: 100.00
+	Hs
		1087411 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP42_HUMAN (86-457): 6.35e-25: 113: 15.76
+	Sc
		355656 H2B1_YEAST (3-125): 1.81e-36: 122: 71.55		IWS1_YEAST (408-804): 1.94e-38: 150: 22.87
+	Hs
		152598 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		KMT2D_HUMAN (8-481): 2.23e-10: 66.8: 13.13
+	Hs
		1087338 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		CHAP1_HUMAN (4-585): 8.55e-10: 64.5: 12.54
+	Hs
		918607 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		CHAP1_HUMAN (4-585): 8.55e-10: 64.5: 12.54
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64
+	Hs
		707710 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		CHAP1_HUMAN (4-585): 8.55e-10: 64.5: 12.54
+	Hs
		617962 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64
+	Hs
		1087299 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64
+	Hs
		1264778 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64
+	Hs
		883041 H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64
+	Hs
		241595 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64
+	Hs
		886166 H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64
+	Hs
		1264792 H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62		TITIN_HUMAN (1-582): 6.22e-09: 62.2: 10.64