HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: UBP42 (Q9H9J4)
Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.4.19.12) (Deubiquitinating enzyme 42) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42)
Gene: USP42

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25336640
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1324
+	Hs
		1087489 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP22_HUMAN (81-413): 1.9e-109: 357: 26.58
+	Hs
		707794 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP22_HUMAN (81-413): 1.9e-109: 357: 26.58
+	Hs
		707665 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP51_HUMAN (106-412): 1.74e-101: 341: 26.29
+	Hs
		259286 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP12_HUMAN (90-403): 1.11e-104: 338: 23.58
+	Hs
		905383 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP46_HUMAN (90-403): 8.36e-105: 338: 24.48
+	Hs
		905394 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		UBP46_HUMAN (90-403): 8.36e-105: 338: 24.48
+	Hs
		271037 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP2_HUMAN (33-417): 1.27e-100: 335: 25.65
+	Dm
		355272 H2B_DROME (36-126): 9.49e-47: 148: 95.60		UBP36_DROME (13-819): 5.11e-102: 351: 22.05
+	Hs
		420851 H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21		UBP48_HUMAN (66-505): 2.07e-91: 321: 18.07
+	Hs
		918483 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		UBP48_HUMAN (66-505): 2.07e-91: 321: 18.07
+	Hs
		918801 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		UBP3_HUMAN (39-413): 1.26e-96: 321: 25.76
+	Hs
		707674 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP48_HUMAN (66-505): 2.07e-91: 321: 18.07
+	Hs
		707807 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP3_HUMAN (39-413): 1.26e-96: 321: 25.76
+	Hs
		1087213 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP49_HUMAN (51-443): 1.21e-87: 302: 21.29
+	Sc
		355943 H2B2_YEAST (3-125): 4.73e-37: 124: 71.55		UBP8_YEAST (109-413): 1.93e-95: 316: 28.19
+	Sc
		355547 H2B1_YEAST (3-125): 1.81e-36: 122: 71.55		UBP8_YEAST (109-413): 1.93e-95: 316: 28.19
+	Hs
		420891 H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21		UBP36_HUMAN (558-1131): 6.82e-10: 66.1: 8.87
+	Hs
		241654 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		UBP36_HUMAN (558-1131): 6.82e-10: 66.1: 8.87
+	Hs
		707772 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP36_HUMAN (558-1131): 6.82e-10: 66.1: 8.87