HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36199071
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 605
+	Hs
		1087323 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		209397 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		420817 H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		903263 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		707570 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		196995 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		1087388 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67
+	Hs
		245607 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TBL1X_HUMAN (501-605): 3.8e-15: 80.4: 19.13
+	At
		189120 H2B1_ARATH (3-125): 2.03e-43: 141: 68.80		GBLPA_ARATH (439-584): 1.06e-09: 62.4: 31.21