HitPredict

Interactor 1: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 855 Hs			1 435
+	Mm
		546292 NTRK2_MOUSE (498-850): 7.48e-107: 349: 40.50		AP2M1_MOUSE (1-435): 1.03e-178: 507: 100.00
+	Hs
		508141 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		508180 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		385470 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		337527 ABL1_HUMAN (557-846): 9.71e-55: 207: 41.03		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Rn
		544815 INSR_RAT (511-849): 4.34e-54: 206: 37.46		AP2M1_RAT (1-435): 1.03e-178: 507: 100.00
+	Hs
		69211 A9UF07_HUMAN (557-846): 4.25e-54: 206: 41.03		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		385759 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66
+	Rn
		544829 INSR_RAT (511-849): 4.34e-54: 206: 37.46		AP1M1_RAT (2-434): 6.49e-170: 484: 38.85
+	Hs
		609222 FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28		AP3M2_HUMAN (1-434): 2.92e-119: 355: 24.89
+	At
		187748 BAME3_ARATH (159-473): 7.5e-29: 126: 6.54		AP2M_ARATH (2-435): 8.67e-160: 459: 47.27
+	Hs
		608213 FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78		STON1_HUMAN (149-408): 2.5e-58: 205: 21.75
+	Hs
		337514 ABL1_HUMAN (557-846): 9.71e-55: 207: 41.03		STON2_HUMAN (146-433): 1.58e-62: 219: 22.85
+	Hs
		69210 A9UF07_HUMAN (557-846): 4.25e-54: 206: 41.03		STON2_HUMAN (146-433): 1.58e-62: 219: 22.85