HitPredict

Interactor 1: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.578

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 855 Hs			1 1129
+	Hs
		508262 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		385705 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		608185 FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		195775 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195776 FYN_HUMAN (548-850): 3.85e-99: 320: 35.64		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		385190 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		DP13B_HUMAN (45-453): 1.01e-98: 329: 16.03
+	Hs
		1083906 NTRK2_HUMAN (498-850): 2.17e-106: 348: 40.50		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		608050 FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78		DP13B_HUMAN (45-453): 1.01e-98: 329: 16.03
+	Hs
		508261 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		385693 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		1081642 NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		608182 FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		385363 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		AGAP3_HUMAN (361-662): 1.44e-59: 223: 27.97
+	Hs
		385364 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		609490 FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		412284 FYN_HUMAN (548-850): 3.85e-99: 320: 35.64		ARAP2_HUMAN (162-622): 8.31e-61: 230: 18.97
+	Hs
		385239 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		ARAP3_HUMAN (368-605): 4.78e-56: 215: 27.46
+	Hs
		508123 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		601555 FGFR2_HUMAN (522-851): 6.41e-102: 336: 34.42		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		608061 FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21