HitPredict

Interactor 1: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005925 - focal adhesion GO:0071456 - cellular response to hypoxia
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 855 Hs			1 999
+	Hs
		508291 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		385786 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		609631 FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		1081658 NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		608207 FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		385266 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		1081553 NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320803 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		320790 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		320811 FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		320862 NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		384373 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		609191 FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		507880 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		507924 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		384372 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		384163 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		503438 FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		507836 FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		384219 NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70