HitPredict

Interactor 1: CUL3 (Q17391)
Cullin-3 (CUL-3)
Gene: cul-3

Interactor 2: Q18986 (Q18986)
BTB domain-containing protein
Gene: CELE_D2045.8

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.523

Property	Details
Experiments	13679922
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Ce			1 238
+	Hs
		1042523 CUL3_HUMAN (1-777): 0: 849: 47.95		BACD3_HUMAN (2-226): 1.11e-77: 238: 34.62
+	Hs
		1041533 CUL3_HUMAN (1-777): 0: 849: 47.95		BACD2_HUMAN (4-226): 4.99e-71: 221: 31.33
+	Hs
		1042165 CUL3_HUMAN (1-777): 0: 849: 47.95		BACD1_HUMAN (2-226): 6.78e-71: 221: 33.62
+	Ce
		1088887 CUL3_CAEEL (1-777): 0: 839: 100.00		Q965M5_CAEEL (2-178): 7.47e-48: 158: 31.29
+	Ce
		184054 CUL3_CAEEL (1-777): 0: 839: 100.00		O16612_CAEEL (3-181): 5.88e-48: 158: 31.32
+	Hs
		1041891 CUL3_HUMAN (1-777): 0: 849: 47.95		KCTD9_HUMAN (4-159): 1.1e-40: 145: 27.50
+	Ce
		109385 CUL3_CAEEL (1-777): 0: 839: 100.00		H2KY83_CAEEL (3-178): 1.39e-46: 154: 29.51
+	Hs
		1041705 CUL3_HUMAN (1-777): 0: 849: 47.95		KCD21_HUMAN (4-100): 1.1e-38: 136: 40.82
+	Ce
		954547 CUL3_CAEEL (1-777): 0: 839: 100.00		P91563_CAEEL (4-173): 1.42e-42: 145: 36.63
+	Hs
		1042096 CUL3_HUMAN (1-777): 0: 849: 47.95		SHKB1_HUMAN (2-107): 2.37e-35: 134: 33.65
+	Hs
		1042934 CUL3_HUMAN (1-777): 0: 849: 47.95		KCTD3_HUMAN (5-121): 4.07e-35: 134: 31.45
+	Hs
		1042035 CUL3_HUMAN (1-777): 0: 849: 47.95		KCD17_HUMAN (5-113): 1.86e-36: 132: 33.33
+	Hs
		1042063 CUL3_HUMAN (1-777): 0: 849: 47.95		KCTD6_HUMAN (4-141): 2.8e-37: 132: 31.66
+	Hs
		1041584 CUL3_HUMAN (1-777): 0: 849: 47.95		KCTD2_HUMAN (4-110): 1.41e-36: 131: 31.53
+	Hs
		1042242 CUL3_HUMAN (1-777): 0: 849: 47.95		KCD12_HUMAN (2-98): 1.76e-35: 130: 38.24
+	Hs
		1041881 CUL3_HUMAN (1-777): 0: 849: 47.95		KCTD1_HUMAN (3-131): 5.37e-36: 129: 28.26
+	Hs
		1042675 CUL3_HUMAN (1-777): 0: 849: 47.95		KCTD5_HUMAN (2-112): 2.32e-35: 127: 29.83
+	Ce
		1088878 CUL3_CAEEL (1-777): 0: 839: 100.00		Q18776_CAEEL (2-107): 3.18e-37: 133: 34.86
+	Hs
		1042309 CUL3_HUMAN (1-777): 0: 849: 47.95		KCTD7_HUMAN (4-119): 4.46e-33: 122: 41.86
+	Hs
		1043508 CUL4B_HUMAN (5-777): 0: 785: 34.11		KCD12_HUMAN (2-98): 1.76e-35: 130: 38.24