HitPredict

Interactor 1: CUL4 (Q17392)
Cullin-4 (CUL-4)
Gene: cul-4

Interactor 2: DDB1 (Q21554)
DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1)
Gene: ddb-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 1.00 0.768

The method score is based on:

Property Details
Experiments 18794348, 17145765
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSF_A~Cullin, Cullin~MMS1_N
Common GO terms GO:0016567 - protein ubiquitination
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 840
Ce

1 1134
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ At
+ Dm
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sp
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024