HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSD11 (O00231)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)
Gene: PSMD11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~RPN6_N
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 422
+	Hs
		121684 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00
+	Hs
		121685 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00
+	Hs
		121635 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00
+	Hs
		121689 PSA5_HUMAN (1-179): 2.12e-66: 204: 31.52		PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00
+	Dm
		771297 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSD11_DROME (4-422): 6.96e-107: 323: 67.46
+	Dm
		1180708 PSA5_DROME (1-179): 2.3e-67: 207: 27.96		PSD11_DROME (4-422): 6.96e-107: 323: 67.46
+	Hs
		637690 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Sc
		771394 PSA4_YEAST (1-178): 5.6e-67: 206: 32.60		RPN6_YEAST (39-421): 4.48e-81: 257: 45.36
+	Dm
		771305 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSMD6_DROME (31-422): 3.38e-72: 233: 13.93
+	Hs
		108945 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Hs
		638133 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Hs
		156291 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Hs
		121936 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	Hs
		656232 PSA5_HUMAN (1-179): 2.12e-66: 204: 31.52		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Dm
		771304 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		CSN4_DROME (36-421): 1.46e-64: 214: 11.88
+	Dm
		1278633 PSA5_DROME (1-179): 2.3e-67: 207: 27.96		PSMD6_DROME (31-422): 3.38e-72: 233: 13.93
+	Hs
		108919 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	Hs
		121938 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	Hs
		121892 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	Hs
		121942 PSA5_HUMAN (1-179): 2.12e-66: 204: 31.52		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86