HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSD12 (O00232)
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)
Gene: PSMD12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 456
+	Hs
		121936 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00
+	Hs
		121938 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00
+	Hs
		121892 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00
+	Hs
		121942 PSA5_HUMAN (1-179): 2.12e-66: 204: 31.52		PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00
+	Hs
		121979 PSA6_HUMAN (2-180): 6.87e-65: 201: 28.73		PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00
+	Sc
		771393 PSA4_YEAST (1-178): 5.6e-67: 206: 32.60		RPN5_YEAST (14-456): 3.37e-106: 324: 40.67
+	Sc
		619398 PSA3_YEAST (1-179): 1.05e-65: 203: 53.63		RPN5_YEAST (14-456): 3.37e-106: 324: 40.67
+	Hs
		121684 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44
+	Dm
		771304 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		CSN4_DROME (45-450): 1.98e-91: 284: 20.00
+	Dm
		771297 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSD11_DROME (28-443): 1.94e-86: 272: 15.21
+	Hs
		893638 PSA6_HUMAN (2-180): 6.87e-65: 201: 28.73		CSN2_HUMAN (24-439): 1.11e-94: 294: 12.59
+	Hs
		108918 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44
+	Hs
		121685 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44
+	Hs
		121635 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44
+	Hs
		121689 PSA5_HUMAN (1-179): 2.12e-66: 204: 31.52		PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44
+	Hs
		121719 PSA6_HUMAN (2-180): 6.87e-65: 201: 28.73		PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44
+	Dm
		1180708 PSA5_DROME (1-179): 2.3e-67: 207: 27.96		PSD11_DROME (28-443): 1.94e-86: 272: 15.21
+	Dm
		574022 PSA4_DROME (1-181): 9.01e-66: 203: 73.37		PSD11_DROME (28-443): 1.94e-86: 272: 15.21
+	Sc
		771394 PSA4_YEAST (1-178): 5.6e-67: 206: 32.60		RPN6_YEAST (26-452): 2.93e-77: 249: 14.48
+	Sc
		619400 PSA3_YEAST (1-179): 1.05e-65: 203: 53.63		RPN6_YEAST (26-452): 2.93e-77: 249: 14.48