Interactor 1: AKT1 (Q17941)
Serine/threonine-protein kinase akt-1 (EC 2.7.11.1) (Protein kinase B akt-1) (PKB akt-1)
Gene: akt-1

Interactor 2: SGK1 (Q2PJ68)
Serine/threonine-protein kinase sgk-1 (EC 2.7.11.1) (Serum- and glucocorticoid-inducible kinase homolog) (Serum/glucocorticoid-regulated kinase 1)
Gene: sgk-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.751

The method score is based on:

Property Details
Experiments 15068796
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 - nucleus
and 7 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 541
Ce

1 463
+ Ce
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024