HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain)
Gene: PSMA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 241
+	Hs
		637631 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA5_HUMAN (1-241): 1.49e-107: 311: 100.00
+	Ss
		94704 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		F2Z5K2_PIG (1-241): 1.49e-107: 311: 100.00
+	Dm
		771303 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSA5_DROME (1-241): 1.3e-103: 301: 70.37
+	Hs
		638067 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA5_HUMAN (1-241): 1.49e-107: 311: 100.00
+	Hs
		637624 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96
+	Hs
		156224 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA7_HUMAN (8-239): 7.45e-89: 264: 36.17
+	Hs
		637316 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81
+	Ss
		94582 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		F1SBA5_PIG (6-235): 1.55e-90: 268: 38.20
+	Hs
		637663 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA6_HUMAN (4-241): 1.93e-88: 263: 25.93
+	Hs
		108925 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96
+	Hs
		637626 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96
+	Hs
		108924 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81
+	Hs
		156226 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA7_HUMAN (8-239): 7.45e-89: 264: 36.17
+	Hs
		637318 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81
+	Hs
		108938 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSA6_HUMAN (4-241): 1.93e-88: 263: 25.93
+	Hs
		638100 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA6_HUMAN (4-241): 1.93e-88: 263: 25.93
+	Hs
		156169 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PSA7_HUMAN (8-239): 7.45e-89: 264: 36.17
+	Hs
		156223 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81
+	Hs
		637719 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSMA8_HUMAN (6-235): 3.19e-44: 150: 37.24
+	Ce
		1278563 PSA4_CAEEL (1-178): 8.98e-71: 216: 64.61		PSA7_CAEEL (6-239): 1.78e-43: 149: 35.29