HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PRS7 (P35998)
26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)
Gene: PSMC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 433
+	Hs
		637639 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS7_HUMAN (1-433): 3.93e-144: 419: 100.00
+	Dm
		771298 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q7KMQ0_DROME (1-433): 1.08e-142: 416: 91.69
+	Hs
		638074 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS7_HUMAN (1-433): 3.93e-144: 419: 100.00
+	Dm
		771287 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PRS4_DROME (1-428): 9.23e-138: 403: 39.30
+	Hs
		156240 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PRS7_HUMAN (1-433): 3.93e-144: 419: 100.00
+	Hs
		637642 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS6B_HUMAN (3-425): 2.12e-121: 361: 35.93
+	Dm
		186105 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PRS8_DROME (29-430): 7.81e-122: 361: 46.52
+	Rn
		566253 PSA2_RAT (1-178): 1.13e-77: 233: 38.76		PRS8_RAT (35-430): 2.5e-119: 355: 45.20
+	Hs
		637668 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS8_HUMAN (35-430): 2.5e-119: 355: 45.20
+	Hs
		637669 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS10_HUMAN (39-429): 1.33e-119: 355: 42.46
+	Dm
		771301 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q8SZ19_DROME (42-429): 3.46e-116: 347: 44.10
+	Dm
		771327 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q9W414_DROME (42-429): 1.84e-116: 347: 44.36
+	Hs
		108931 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PRS6B_HUMAN (3-425): 2.12e-121: 361: 35.93
+	Hs
		638078 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS6B_HUMAN (3-425): 2.12e-121: 361: 35.93
+	Hs
		156245 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PRS6B_HUMAN (3-425): 2.12e-121: 361: 35.93
+	Hs
		108940 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PRS8_HUMAN (35-430): 2.5e-119: 355: 45.20
+	Hs
		108941 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PRS10_HUMAN (39-429): 1.33e-119: 355: 42.46
+	Hs
		638105 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS8_HUMAN (35-430): 2.5e-119: 355: 45.20
+	Hs
		638107 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS10_HUMAN (39-429): 1.33e-119: 355: 42.46
+	Hs
		156271 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		PRS10_HUMAN (39-429): 1.33e-119: 355: 42.46