HitPredict

Interactor 1: RHG44 (Q17R89)
Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2)
Gene: ARHGAP44

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 818 Hs			1 665
+	Hs
		1089312 RHG44_HUMAN (1-818): 1.01e-156: 479: 100.00		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		1148382 RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		1148393 RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		1285232 3BP1_HUMAN (1-589): 2.97e-86: 290: 39.22		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		1191674 SRGP1_HUMAN (12-751): 2.95e-75: 267: 15.13		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		1377711 3BP1_HUMAN (1-589): 2.97e-86: 290: 39.22		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		1066027 RHG44_HUMAN (1-818): 1.01e-156: 479: 100.00		ARHG6_HUMAN (218-345): 4.37e-16: 84.3: 24.81
+	Hs
		924636 RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		1148372 RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34		DNMBP_HUMAN (104-607): 3.03e-16: 85.1: 15.82
+	Hs
		253361 SRGP2_HUMAN (12-782): 1.01e-71: 256: 15.15		SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72
+	Hs
		557642 CHIO_HUMAN (30-429): 4.28e-88: 288: 17.93		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		551038 CHIN_HUMAN (30-429): 8.69e-84: 277: 16.94		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		200212 SRGP3_HUMAN (12-710): 4.72e-73: 261: 14.75		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		64651 RHG32_HUMAN (223-748): 1.81e-69: 252: 20.14		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		253421 SRGP2_HUMAN (12-782): 1.01e-71: 256: 15.15		ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30
+	Hs
		209014 CHIO_HUMAN (30-429): 4.28e-88: 288: 17.93		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Hs
		208987 CHIN_HUMAN (30-429): 8.69e-84: 277: 16.94		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Hs
		1049716 SRGP1_HUMAN (12-751): 2.95e-75: 267: 15.13		ARHG7_HUMAN (228-354): 4.83e-14: 77.8: 20.31
+	Hs
		64627 RHG32_HUMAN (223-748): 1.81e-69: 252: 20.14		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Hs
		253384 SRGP2_HUMAN (12-782): 1.01e-71: 256: 15.15		SH3R3_HUMAN (197-627): 1.12e-12: 73.6: 12.19