HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSB3 (P49720)
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)
Gene: PSMB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 205
+	Hs
		637648 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB3_HUMAN (1-205): 1.02e-71: 218: 100.00
+	Hs
		637633 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB6_HUMAN (7-200): 4.63e-70: 215: 22.68
+	Dm
		771285 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSB1_DROME (2-205): 3.62e-70: 215: 26.51
+	Hs
		637629 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB8_HUMAN (8-205): 2.05e-67: 209: 22.73
+	Ss
		94705 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		G3DRF8_PIG (7-200): 1.52e-69: 213: 22.17
+	Hs
		637634 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB5_HUMAN (8-197): 1.9e-66: 206: 22.63
+	Hs
		594448 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB1_HUMAN (2-205): 1.85e-65: 203: 23.94
+	Dm
		771328 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSB3_DROME (1-205): 1.69e-67: 207: 63.90
+	Dm
		771294 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q7K148_DROME (8-195): 1.2e-65: 205: 23.94
+	Dm
		47598 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		A0AQH0_DROME (7-199): 4.68e-66: 204: 24.35
+	Hs
		637624 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA2_HUMAN (8-205): 1.92e-64: 200: 14.85
+	Dm
		184454 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		O17311_DROME (3-196): 7.34e-65: 203: 20.10
+	Hs
		637631 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA5_HUMAN (8-203): 6.92e-64: 199: 12.20
+	Hs
		637630 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB9_HUMAN (6-200): 1.41e-63: 197: 23.08
+	Dm
		771302 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q8T8V8_DROME (8-196): 7.46e-64: 201: 20.11
+	Hs
		638065 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSB8_HUMAN (8-205): 2.05e-67: 209: 22.73
+	Hs
		594450 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSB1_HUMAN (2-205): 1.85e-65: 203: 23.94
+	Hs
		637626 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA2_HUMAN (8-205): 1.92e-64: 200: 14.85
+	Ph
		223381 PSA_PYRHO (2-178): 1.92e-70: 215: 41.24		PSB1_PYRHO (5-202): 8.05e-64: 197: 25.63
+	Hs
		638066 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSB9_HUMAN (6-200): 1.41e-63: 197: 23.08