HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSA6 (P60900)
Proteasome subunit alpha type-6 (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain)
Gene: PSMA6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 181 Hs			1 246
+	Hs
		637663 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA6_HUMAN (1-246): 2.11e-110: 319: 100.00
+	Hs
		637624 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA2_HUMAN (7-243): 8.3e-104: 302: 35.44
+	Hs
		638100 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA6_HUMAN (1-246): 2.11e-110: 319: 100.00
+	Dm
		771329 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSA6_DROME (1-246): 2.12e-101: 296: 66.67
+	Hs
		156224 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA7_HUMAN (9-240): 1.34e-97: 286: 33.62
+	Ss
		94582 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		F1SBA5_PIG (6-236): 9.13e-98: 287: 32.47
+	Hs
		108925 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSA2_HUMAN (7-243): 8.3e-104: 302: 35.44
+	Hs
		637631 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA5_HUMAN (1-242): 4.79e-96: 282: 25.91
+	Hs
		637316 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA1_HUMAN (1-245): 2.4e-94: 279: 25.91
+	Ss
		94704 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		F2Z5K2_PIG (1-242): 4.79e-96: 282: 25.91
+	Dm
		771303 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSA5_DROME (1-243): 1.36e-95: 281: 26.40
+	Hs
		637719 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSMA8_HUMAN (6-240): 1.87e-93: 276: 29.46
+	Hs
		637626 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA4_HUMAN (6-239): 5.7e-93: 275: 32.35
+	Hs
		156226 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA7_HUMAN (9-240): 1.34e-97: 286: 33.62
+	Hs
		108927 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSA5_HUMAN (1-242): 4.79e-96: 282: 25.91
+	Hs
		638067 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA5_HUMAN (1-242): 4.79e-96: 282: 25.91
+	Hs
		108924 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PSA1_HUMAN (1-245): 2.4e-94: 279: 25.91
+	Hs
		637318 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA1_HUMAN (1-245): 2.4e-94: 279: 25.91
+	Hs
		638061 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA4_HUMAN (6-239): 5.7e-93: 275: 32.35