HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 406
+	At
		286458 PSA4A_ARATH (1-179): 1.87e-73: 223: 61.45		PRS4A_ARATH (19-396): 1.25e-158: 455: 47.62
+	Dm
		771287 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PRS4_DROME (4-396): 3.02e-138: 403: 45.04
+	Rn
		566253 PSA2_RAT (1-178): 1.13e-77: 233: 38.76		PRS8_RAT (1-406): 1.42e-136: 398: 100.00
+	Hs
		637668 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00
+	Hs
		637667 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31
+	Hs
		638105 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00
+	Hs
		638104 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31
+	Hs
		637642 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86
+	Dm
		771310 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q9V405_DROME (7-399): 9.79e-122: 360: 41.73
+	Hs
		637639 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31
+	Hs
		108931 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86
+	Hs
		638078 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86
+	Dm
		771298 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q7KMQ0_DROME (81-392): 1.77e-115: 345: 55.45
+	Hs
		108930 H0YKT8_HUMAN (1-181): 8.06e-71: 213: 100.00		PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31
+	Hs
		638074 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31
+	Hs
		637669 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64
+	Dm
		186105 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PRS8_DROME (8-123): 6.29e-11: 65.5: 7.76
+	Dm
		771327 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q9W414_DROME (8-101): 2.04e-10: 64: 10.64
+	Dm
		771301 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q8SZ19_DROME (8-97): 2.57e-10: 63.6: 10.00
+	Hs
		638107 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64