HitPredict

Interactor 1: Q18477 (Q18477)
Histone deacetylase domain-containing protein
Gene: hda-11

Interactor 2: CES2 (Q94126)
Transcription factor ces-2 (Cell death specification protein 2)
Gene: ces-2

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Ce			1 211
+	Mm
		140216 HDAC1_MOUSE (13-314): 1.61e-131: 385: 21.59		JUNB_MOUSE (3-182): 2.91e-25: 102: 16.33
+	Hs
		831885 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		CEBPD_HUMAN (97-183): 6.32e-25: 99.9: 26.44
+	Hs
		569696 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		CEBPB_HUMAN (83-188): 4.58e-24: 99.2: 23.59
+	Mm
		140244 HDAC1_MOUSE (13-314): 1.61e-131: 385: 21.59		CEBPA_MOUSE (113-183): 9.51e-23: 95.6: 29.58
+	Mm
		140234 HDAC1_MOUSE (13-314): 1.61e-131: 385: 21.59		CEBPB_MOUSE (113-188): 3.04e-22: 93.4: 30.26
+	Hs
		401956 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		JUN_HUMAN (3-182): 2.96e-22: 94.2: 16.43
+	Hs
		579204 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		ATF3_HUMAN (50-198): 5.73e-23: 92.7: 16.78
+	Hs
		831299 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		CEBPA_HUMAN (78-187): 2.38e-20: 89.2: 21.82
+	Dm
		599218 HDAC1_DROME (14-316): 2.39e-129: 381: 21.20		FOSLA_DROME (62-186): 7.85e-21: 91.9: 21.60
+	Mm
		450547 HDAC2_MOUSE (10-314): 8.3e-121: 358: 21.07		JUNB_MOUSE (3-182): 2.91e-25: 102: 16.33
+	Hs
		569923 HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76		CEBPB_HUMAN (83-188): 4.58e-24: 99.2: 23.59
+	Mm
		862804 HDAC2_MOUSE (10-314): 8.3e-121: 358: 21.07		CEBPA_MOUSE (113-183): 9.51e-23: 95.6: 29.58
+	Hs
		402302 HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76		JUN_HUMAN (3-182): 2.96e-22: 94.2: 16.43
+	Ce
		105173 HDA1_CAEEL (6-314): 1.4e-121: 359: 21.43		FOS1_CAEEL (38-179): 2.82e-21: 92.7: 14.79
+	Sp
		223487 CLR6_SCHPO (16-318): 1.46e-120: 354: 21.77		ATF1_SCHPO (16-195): 1.17e-22: 96.9: 16.85
+	Hs
		831536 HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76		CEBPA_HUMAN (78-187): 2.38e-20: 89.2: 21.82
+	Mm
		936396 HDAC2_MOUSE (10-314): 8.3e-121: 358: 21.07		ATF3_MOUSE (50-198): 3.08e-21: 88.4: 16.78
+	Rn
		403726 HDAC3_RAT (17-314): 2e-118: 350: 21.47		CEBPA_RAT (113-183): 1.36e-22: 95.3: 29.58
+	Hs
		177168 HDAC3_HUMAN (17-314): 2.9e-118: 349: 21.47		JUN_HUMAN (3-182): 2.96e-22: 94.2: 16.43
+	Ce
		1090091 Q18477_CAEEL (1-334): 7.24e-125: 363: 100.00		Q9NAE4_CAEEL (108-177): 7.2e-14: 68.7: 41.43