Interactor 1: KPC3 (Q19266)
Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein kinase C-3) (aPKC3)
Gene: pkc-3

Interactor 2: PAR6 (Q9NAN2)
Partitioning defective protein 6
Gene: par-6

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 16996049, 28829947, 20122916, 20579886, 26912668, 26780296, 18502617, 14704431, unassigned1274
Identification Methods two hybrid, biochemical, affinity chromatography technology, protein complementation assay, mammalian protein protein interaction trap, two hybrid pooling approach
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~PB1, PB1~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005938 - cell cortex
GO:0007163 - establishment or maintenance of cell polarity
GO:0007338 - single fertilization
GO:0007369 - gastrulation
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 597
Ce

1 309
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Ce
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024