HitPredict

Interactor 1: Q1EC57 (Q1EC57)
COP9 signalosome complex subunit 6
Gene: Q1EC57

Interactor 2: CSN5A (Q8LAZ7)
COP9 signalosome complex subunit 5a (Signalosome subunit 5a) (EC 3.4.-.-) (Jun activation domain-binding homolog 1)
Gene: CSN5A

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21798944
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CSN5_C~JAB, JAB~JAB, CSN5_C~MitMem_reg, JAB~MitMem_reg
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0008237 - metallopeptidase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 At			1 357
+	At
		1227248 CSN6A_ARATH (1-317): 1.18e-122: 356: 100.00		CSN5A_ARATH (1-357): 2.09e-139: 401: 100.00
+	At
		1227247 CSN6B_ARATH (1-317): 2.85e-122: 355: 87.38		CSN5A_ARATH (1-357): 2.09e-139: 401: 100.00
+	At
		1258863 CSN6A_ARATH (1-317): 1.18e-122: 356: 100.00		CSN5B_ARATH (1-356): 1.45e-134: 389: 85.71
+	At
		1258851 CSN6B_ARATH (1-317): 2.85e-122: 355: 87.38		CSN5B_ARATH (1-356): 1.45e-134: 389: 85.71
+	Dm
		1363294 CSN6_DROME (1-307): 8.35e-101: 301: 37.42		CSN5_DROME (6-342): 6.46e-129: 373: 63.80
+	Hs
		1184934 CSN6_HUMAN (1-307): 9.13e-106: 313: 37.86		CSN5_HUMAN (1-338): 6.45e-123: 359: 65.09
+	Mm
		193510 CSN6_MOUSE (1-307): 9.6e-105: 310: 37.86		CSN5_MOUSE (1-338): 4.4e-123: 359: 65.09
+	Hs
		124919 EIF3F_HUMAN (1-297): 9.85e-97: 291: 24.00		CSN5_HUMAN (1-338): 6.45e-123: 359: 65.09
+	Hs
		72127 B3KSH1_HUMAN (1-297): 1.09e-96: 292: 24.00		EIF3H_HUMAN (51-350): 7.18e-84: 260: 16.89
+	Hs
		124674 EIF3F_HUMAN (1-297): 9.85e-97: 291: 24.00		EIF3H_HUMAN (51-350): 7.18e-84: 260: 16.89
+	Dm
		640778 PSMD7_DROME (1-312): 4.72e-92: 278: 21.56		PSDE_DROME (42-312): 2.1e-83: 257: 33.33
+	Hs
		177079 Q9BX72_HUMAN (1-296): 8.48e-89: 270: 22.00		EIF3H_HUMAN (51-350): 7.18e-84: 260: 16.89
+	Hs
		130804 PSMD7_HUMAN (7-308): 1.83e-89: 272: 21.36		PSDE_HUMAN (49-312): 3.09e-81: 251: 32.98
+	Dm
		1353828 EI3F1_DROME (5-303): 6.74e-91: 273: 18.75		EIF3H_DROME (41-350): 2.31e-78: 245: 17.63
+	Ce
		247771 O61792_CAEEL (7-315): 8.88e-85: 261: 21.59		PSDE_CAEEL (49-312): 6.42e-75: 235: 30.85
+	Sp
		251460 RPN8_SCHPO (1-300): 7.03e-79: 245: 22.29		RPN11_SCHPO (37-310): 7.7e-76: 237: 29.87
+	Hs
		124660 EIF3F_HUMAN (1-297): 9.85e-97: 291: 24.00		EIF3F_HUMAN (40-293): 1.16e-53: 182: 12.27
+	Sc
		797613 RPN8_YEAST (9-312): 1.25e-73: 231: 19.76		RPN11_YEAST (37-311): 1e-76: 240: 30.41
+	Hs
		849163 PSMD7_HUMAN (7-308): 1.83e-89: 272: 21.36		PSMD7_HUMAN (55-281): 1.01e-56: 189: 16.80
+	Sc
		996265 RPN8_YEAST (9-312): 1.25e-73: 231: 19.76		RPN8_YEAST (57-211): 2.34e-29: 117: 22.79