Interactor 1: DOXA2 (Q1HG44)
Dual oxidase maturation factor 2 (Dual oxidase activator 2)
Gene: DUOXA2

Interactor 2: DUOX2 (Q9NRD8)
Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (Large NOX 2) (Long NOX 2) (NADH/NADPH thyroid oxidase p138-tox) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (p138 thyroid oxidase)
Gene: DUOX2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.690

The method score is based on:

Property Details
Experiments 25761904
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, comigration in non denaturing gel electrophoresis
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains An_peroxidase~DuoxA, DuoxA~Ferric_reduct
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0031252 - cell leading edge
GO:0045177 - apical part of cell
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 320
Hs

1 1548
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024