Interactor 1: LIN41 (Q1PSW8)
E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71)
Gene: Trim71

Interactor 2: AGO2 (Q8CJG0)
Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer)
Gene: AGO2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 19898466
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000932 - P-body
GO:0035196 - miRNA processing
GO:0035198 - miRNA binding
GO:0035278 - miRNA-mediated gene silencing by inhibition of translation
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 855
Mm

1 860
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024