HitPredict

Interactor 1: GDIR (Q20496)
Probable rho GDP-dissociation inhibitor (Rho GDI)
Gene: rhi-1

Interactor 2: RHO1 (Q22038)
Ras-like GTP-binding protein rhoA
Gene: rho-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10583406
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~Rho_GDI
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Ce			1 192
+	Hs
		854769 GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17		RAC1_HUMAN (1-192): 5.49e-81: 240: 58.76
+	Mm
		925816 GDIR1_MOUSE (6-191): 1.59e-95: 277: 38.71		RAC1_MOUSE (1-192): 5.49e-81: 240: 58.76
+	Rn
		901290 GDIR1_RAT (6-191): 1.59e-95: 277: 38.71		RHOA_RAT (1-192): 7.42e-80: 237: 88.08
+	Hs
		854763 GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17		RHOA_HUMAN (1-192): 2.88e-79: 236: 87.57
+	Hs
		854771 GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17		RHOG_HUMAN (1-192): 2.68e-78: 233: 55.73
+	Hs
		545278 GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17		RAC2_HUMAN (1-192): 1.63e-77: 231: 55.67
+	Hs
		436218 GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17		RHOC_HUMAN (1-192): 3.71e-77: 230: 84.46
+	Hs
		854851 GDIR2_HUMAN (12-191): 4.68e-91: 266: 42.22		RAC1_HUMAN (1-192): 5.49e-81: 240: 58.76
+	Hs
		854760 GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17		CDC42_HUMAN (1-192): 4.64e-76: 228: 52.85
+	Hs
		854759 GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17		RAC3_HUMAN (1-179): 1.4e-75: 226: 58.66
+	Hs
		854767 GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17		RHOB_HUMAN (1-190): 2.32e-75: 226: 80.53
+	Mm
		892716 GDIR1_MOUSE (6-191): 1.59e-95: 277: 38.71		RAC3_MOUSE (1-179): 1.4e-75: 226: 58.66
+	Hs
		854852 GDIR2_HUMAN (12-191): 4.68e-91: 266: 42.22		RHOG_HUMAN (1-192): 2.68e-78: 233: 55.73
+	Hs
		925561 GDIR3_HUMAN (10-191): 1.18e-87: 258: 35.71		RAC1_HUMAN (1-192): 5.49e-81: 240: 58.76
+	Hs
		545279 GDIR2_HUMAN (12-191): 4.68e-91: 266: 42.22		RAC2_HUMAN (1-192): 1.63e-77: 231: 55.67
+	Hs
		900840 GDIR3_HUMAN (10-191): 1.18e-87: 258: 35.71		RHOA_HUMAN (1-192): 2.88e-79: 236: 87.57
+	Hs
		854847 GDIR2_HUMAN (12-191): 4.68e-91: 266: 42.22		RAC3_HUMAN (1-179): 1.4e-75: 226: 58.66
+	Mm
		892713 GDIR2_MOUSE (5-191): 7.55e-90: 263: 38.50		RAC3_MOUSE (1-179): 1.4e-75: 226: 58.66
+	Hs
		894357 GDIR3_HUMAN (10-191): 1.18e-87: 258: 35.71		CDC42_HUMAN (1-192): 4.64e-76: 228: 52.85
+	Hs
		915920 GDIR3_HUMAN (10-191): 1.18e-87: 258: 35.71		RHOB_HUMAN (1-190): 2.32e-75: 226: 80.53