HitPredict

Interactor 1: Q20874 (Q20874)
RBR-type E3 ubiquitin transferase (EC 2.3.2.31)
Gene: CELE_F56D2.2

Interactor 2: UBC18 (Q21633)
Ubiquitin-conjugating enzyme E2 ubc-18 (EC 2.3.2.23)
Gene: ubc-18

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.806

The method score is based on:

Property Details
Experiments 19123269, 16457801
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IBR~UQ_con, RWD~UQ_con
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 484
Ce

1 153
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024