Interactor 1: Q21829 (Q21829)
ATP-dependent DNA helicase II subunit 2 (EC 3.6.4.12)
Gene: cku-80

Interactor 2: Q9U2D2 (Q9U2D2)
Ku domain-containing protein
Gene: cku-70

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 12679813, 11778048, 14704431
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ku~Ku, Ku~Ku_C, Ku~Ku_N, Ku_C~Ku_PK_bind
Common GO terms GO:0000723 - telomere maintenance
GO:0003684 - damaged DNA binding
GO:0003690 - double-stranded DNA binding
GO:0005524 - ATP binding
GO:0006281 - DNA repair
and 4 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 713
Ce

1 679
+ Hs
+ Hs
+ At
+ Hs
+ Dm
+ Sp
+ Sc
+ Sc

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Last updated: 15 Jul 2024