HitPredict

Interactor 1: EGL13 (Q23045)
Transcription factor egl-13 (Protein egg laying defective 13)
Gene: egl-13

Interactor 2: Q86PJ4 (Q86PJ4)
Nuclear Hormone Receptor family (Nuclear receptor NHR-105)
Gene: nhr-105

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 470 Ce			1 429
+	Ce
		1095156 EGL13_CAEEL (1-470): 0: 553: 100.00		Q3LQX0_CAEEL (1-429): 5.37e-114: 341: 93.94
+	Ce
		109789 EGL13_CAEEL (1-470): 0: 553: 100.00		H2KZA1_CAEEL (6-424): 7e-87: 277: 19.41
+	Ce
		106981 EGL13_CAEEL (1-470): 0: 553: 100.00		NH114_CAEEL (25-429): 3.66e-83: 262: 19.77
+	Ce
		1095158 EGL13_CAEEL (1-470): 0: 553: 100.00		Q7KX66_CAEEL (10-141): 1.76e-22: 97.4: 36.69
+	Ce
		1095161 EGL13_CAEEL (1-470): 0: 553: 100.00		Q86PI8_CAEEL (38-147): 3.68e-20: 92: 41.74
+	Ce
		1089857 EGL13_CAEEL (1-470): 0: 553: 100.00		NHR31_CAEEL (24-333): 7.29e-15: 78.6: 24.32
+	Ce
		1088802 EGL13_CAEEL (1-470): 0: 553: 100.00		NHR47_CAEEL (35-128): 3.14e-14: 76.6: 42.27
+	Hs
		233806 HBP1_HUMAN (150-408): 1.95e-51: 183: 23.27		ESR1_HUMAN (3-422): 3.83e-93: 294: 15.88
+	Hs
		370101 BBX_HUMAN (308-470): 2.05e-40: 156: 20.83		ESR1_HUMAN (3-422): 3.83e-93: 294: 15.88
+	Hs
		490111 CIC_HUMAN (183-464): 5.04e-36: 144: 17.00		COT1_HUMAN (2-424): 6.87e-98: 301: 16.79
+	Hs
		782638 CIC_HUMAN (183-464): 5.04e-36: 144: 17.00		HNF4A_HUMAN (2-424): 1.08e-96: 299: 19.15
+	Hs
		782669 TF7L2_HUMAN (189-433): 1.49e-35: 141: 17.55		HNF4A_HUMAN (2-424): 1.08e-96: 299: 19.15
+	Mm
		830721 TF7L2_MOUSE (189-433): 1.39e-37: 144: 17.55		HNF4A_MOUSE (2-424): 4.98e-95: 295: 19.39
+	Hs
		370251 CIC_HUMAN (183-464): 5.04e-36: 144: 17.00		ESR1_HUMAN (3-422): 3.83e-93: 294: 15.88
+	Mm
		587110 TF7L1_MOUSE (189-457): 1.24e-36: 143: 14.39		ESR1_MOUSE (3-422): 7.37e-91: 288: 15.88
+	Hs
		622826 CIC_HUMAN (183-464): 5.04e-36: 144: 17.00		COT2_HUMAN (27-424): 8.31e-92: 285: 18.09
+	Hs
		1264299 BBX_HUMAN (308-470): 2.05e-40: 156: 20.83		ESR2_HUMAN (24-422): 5.28e-85: 271: 18.70
+	Hs
		1301017 CIC_HUMAN (183-464): 5.04e-36: 144: 17.00		NR2E1_HUMAN (24-424): 8.13e-88: 274: 17.85
+	Hs
		1269413 CIC_HUMAN (183-464): 5.04e-36: 144: 17.00		ESR2_HUMAN (24-422): 5.28e-85: 271: 18.70
+	Hs
		1269929 SOX13_HUMAN (222-448): 3.16e-34: 137: 37.00		ESR2_HUMAN (24-422): 5.28e-85: 271: 18.70