HitPredict

Interactor 1: SNAP (Q23983)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein)
Gene: alphaSnap

Interactor 2: Q9VR90 (Q9VR90)
Syntaxin 16
Gene: Syx16

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.860

Property	Details
Experiments	12414991, 14605208, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SNAP~SNARE
Common GO terms	GO:0000149 - SNARE binding GO:0006886 - intracellular protein transport GO:0007269 - neurotransmitter secretion GO:0016020 - membrane GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 292 Dm			1 352
+	Dm
		1095562 SNAP_DROME (1-292): 3.38e-109: 320: 100.00		Q86P91_DROME (1-343): 3.09e-79: 249: 100.00
+	Hs
		152174 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		STX16_HUMAN (1-330): 1.04e-57: 191: 34.38
+	Hs
		898845 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		STX1B_HUMAN (27-351): 2.88e-57: 189: 16.31
+	Hs
		699286 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		STX2_HUMAN (41-350): 1.03e-56: 188: 14.52
+	Hs
		1083986 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		STX1A_HUMAN (27-352): 4.99e-56: 186: 16.56
+	Hs
		152142 SNAA_HUMAN (17-290): 2.88e-106: 312: 61.68		STX16_HUMAN (1-330): 1.04e-57: 191: 34.38
+	Dm
		1095554 SNAP_DROME (1-292): 3.38e-109: 320: 100.00		STX1A_DROME (30-351): 3.14e-54: 181: 15.64
+	Rn
		699171 SNAA_RAT (17-290): 2.01e-106: 313: 62.41		STX1A_RAT (27-352): 9.27e-57: 188: 16.56
+	Dm
		1095553 SNAP_DROME (1-292): 3.38e-109: 320: 100.00		STX5_DROME (1-334): 6.22e-52: 180: 16.37
+	Mm
		192858 SNAA_MOUSE (17-290): 3.11e-106: 312: 62.77		STX1A_MOUSE (27-352): 7.25e-57: 188: 16.56
+	Hs
		1027559 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		STX5_HUMAN (1-333): 1.69e-49: 171: 16.47
+	Hs
		1017786 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		STX4_HUMAN (13-350): 4.35e-48: 165: 14.75
+	Hs
		873539 SNAA_HUMAN (17-290): 2.88e-106: 312: 61.68		STX5_HUMAN (1-333): 1.69e-49: 171: 16.47
+	Hs
		873535 SNAA_HUMAN (17-290): 2.88e-106: 312: 61.68		STX4_HUMAN (13-350): 4.35e-48: 165: 14.75
+	Hs
		178768 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		STX7_HUMAN (94-352): 1.3e-45: 158: 21.46
+	Hs
		1205369 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		STX12_HUMAN (89-337): 3.66e-44: 155: 20.16
+	Hs
		178454 SNAA_HUMAN (17-290): 2.88e-106: 312: 61.68		STX7_HUMAN (94-352): 1.3e-45: 158: 21.46
+	Hs
		1328433 SNAB_HUMAN (4-290): 1.41e-108: 318: 62.37		X5D7S1_HUMAN (203-351): 6.92e-43: 150: 20.81
+	Dm
		1095561 SNAP_DROME (1-292): 3.38e-109: 320: 100.00		Q7K0X9_DROME (103-350): 2.06e-20: 91.5: 21.43
+	Dm
		1095585 SNAP_DROME (1-292): 3.38e-109: 320: 100.00		Q9VU45_DROME (216-352): 3.98e-14: 73.8: 25.00