HitPredict

Interactor 1: DYL1 (Q24117)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (Cut up protein)
Gene: ctp

Interactor 2: DYIN (Q24246)
Cytoplasmic dynein 1 intermediate chain (DH IC) (Dynein intermediate chain, cytosolic) (Protein short wing)
Gene: sw

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.930

Property	Details
Experiments	15581372, 11914076, 17428790, 17570393, 16949604
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	Dynein_IC2~Dynein_light
Common GO terms	GO:0005868 - cytoplasmic dynein complex GO:0005874 - microtubule GO:0007291 - sperm individualization GO:0032991 - protein-containing complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 89 Dm			1 663
+	Hs
		148059 DYL1_HUMAN (1-89): 2.53e-46: 144: 94.38		DC1I1_HUMAN (2-661): 9.6e-111: 349: 46.34
+	Mm
		291681 DYL1_MOUSE (1-89): 2.53e-46: 144: 94.38		DC1I1_MOUSE (2-661): 4.48e-111: 349: 46.68
+	Hs
		148093 DYL2_HUMAN (1-89): 1.65e-45: 142: 96.63		DC1I1_HUMAN (2-661): 9.6e-111: 349: 46.34
+	Hs
		928281 DYL1_HUMAN (1-89): 2.53e-46: 144: 94.38		DC1I2_HUMAN (2-661): 1.59e-107: 340: 46.46
+	Hs
		1033319 DYL2_HUMAN (1-89): 1.65e-45: 142: 96.63		DC1I2_HUMAN (2-661): 1.59e-107: 340: 46.46
+	Ce
		219878 DYL1_CAEEL (1-89): 9.54e-46: 143: 94.38		O45087_CAEEL (3-662): 3.26e-103: 329: 34.18
+	Hs
		928426 DYL1_HUMAN (1-89): 2.53e-46: 144: 94.38		DC2I2_HUMAN (224-657): 6.56e-93: 299: 21.70
+	Hs
		1290452 DYL2_HUMAN (1-89): 1.65e-45: 142: 96.63		DC2I2_HUMAN (224-657): 6.56e-93: 299: 21.70
+	Cr
		65477 A8IRP4_CHLRE (13-88): 1.64e-25: 93: 46.99		A8IJZ3_CHLRE (169-649): 2.88e-99: 316: 20.83
+	Hs
		928277 DYL1_HUMAN (1-89): 2.53e-46: 144: 94.38		STRN3_HUMAN (23-631): 6.19e-77: 263: 14.40
+	Hs
		1022851 DYL2_HUMAN (1-89): 1.65e-45: 142: 96.63		STRN3_HUMAN (23-631): 6.19e-77: 263: 14.40
+	Hs
		792964 DYL1_HUMAN (1-89): 2.53e-46: 144: 94.38		LIS1_HUMAN (498-650): 8.7e-33: 133: 15.69
+	Hs
		793023 DYL2_HUMAN (1-89): 1.65e-45: 142: 96.63		LIS1_HUMAN (498-650): 8.7e-33: 133: 15.69
+	Hs
		928412 DYL1_HUMAN (1-89): 2.53e-46: 144: 94.38		DC2I1_HUMAN (309-654): 1.12e-27: 121: 19.91
+	Hs
		1261759 DYL2_HUMAN (1-89): 1.65e-45: 142: 96.63		DC2I1_HUMAN (309-654): 1.12e-27: 121: 19.91