HitPredict

Interactor 1: H2KYX3 (H2KYX3)
FERM domain-containing protein
Gene: nfm-1

Interactor 2: SPK1 (Q03563)
Serine/threonine-protein kinase spk-1 (EC 2.7.11.1)
Gene: spk-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	26780296, unassigned1274
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 709 Ce			1 1003
+	Ce
		107150 G5EES2_CAEEL (10-509): 1.62e-121: 376: 34.85		SPK1_CAEEL (1-1003): 0: 741: 100.00
+	Ce
		104023 G5EBK3_CAEEL (14-509): 2.77e-121: 375: 34.93		SPK1_CAEEL (1-1003): 0: 741: 100.00
+	Dm
		112344 MERH_DROME (8-647): 7.19e-131: 402: 32.25		M9MS50_DROME (268-908): 2.25e-119: 388: 34.90
+	Dm
		1098333 MERH_DROME (8-647): 7.19e-131: 402: 32.25		Q9VNV0_DROME (268-907): 7.62e-117: 380: 37.17
+	Hs
		204634 E41L2_HUMAN (7-679): 7.86e-122: 389: 17.30		CLK2_HUMAN (742-912): 1.58e-64: 228: 28.16
+	Hs
		204649 E41L2_HUMAN (7-679): 7.86e-122: 389: 17.30		SRPK2_HUMAN (635-906): 7.06e-62: 225: 45.79
+	Hs
		833973 E41L1_HUMAN (7-501): 4.66e-117: 373: 22.42		CLK2_HUMAN (742-912): 1.58e-64: 228: 28.16
+	Hs
		942946 E41LB_HUMAN (11-592): 1.57e-116: 373: 17.05		SRPK2_HUMAN (635-906): 7.06e-62: 225: 45.79
+	Hs
		942948 E41L1_HUMAN (7-501): 4.66e-117: 373: 22.42		SRPK2_HUMAN (635-906): 7.06e-62: 225: 45.79
+	Hs
		834122 E41L1_HUMAN (7-501): 4.66e-117: 373: 22.42		CLK3_HUMAN (741-914): 4.47e-61: 222: 28.25
+	Hs
		505554 EPB41_HUMAN (9-448): 3.63e-121: 384: 20.40		CDK2_HUMAN (720-916): 1.19e-59: 208: 23.38
+	Dm
		830217 MERH_DROME (8-647): 7.19e-131: 402: 32.25		MNB_DROME (731-911): 6.32e-47: 183: 27.32
+	Hs
		414785 MERL_HUMAN (1-647): 1.45e-125: 387: 32.52		CDK1_HUMAN (633-907): 2.14e-55: 196: 20.07
+	Hs
		625121 MOES_HUMAN (11-653): 3.77e-118: 368: 29.78		CDK2_HUMAN (720-916): 1.19e-59: 208: 23.38
+	Hs
		166562 PTN14_HUMAN (4-687): 2.71e-127: 408: 16.32		DCLK1_HUMAN (710-982): 1.14e-38: 157: 14.78
+	Mm
		640208 RADI_MOUSE (11-647): 7.11e-123: 380: 30.22		MYLK_MOUSE (691-978): 1.78e-31: 136: 11.30
+	Hs
		719470 MERL_HUMAN (1-647): 1.45e-125: 387: 32.52		PAK1_HUMAN (714-905): 3.54e-27: 119: 18.97
+	Hs
		833995 E41L3_HUMAN (344-679): 8.69e-10: 64.2: 10.71		CLK2_HUMAN (742-912): 1.58e-64: 228: 28.16