Interactor 1: ORC2 (Q24168)
Origin recognition complex subunit 2 (DmORC2)
Gene: ORC2

Interactor 2: ORC5 (Q24169)
Origin recognition complex subunit 5
Gene: ORC5

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 27016737, 18955499, 24137536, 26139588, 9363940, 29899147, 25762138, 32848132
Identification Methods affinity chromatography technology, pull down, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_16~ORC2, ORC2~ORC5_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005664 - nuclear origin of replication recognition complex
GO:0006260 - DNA replication
GO:0006261 - DNA-templated DNA replication
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 618
Dm

1 460
+ Dm
+ Hs
+ Dm
+ Dm
+ Sp
+ Hs
+ Hs
+ Hs
+ Sc
+ At
+ Sp
+ Sp
+ Sp
+ At
+ Sc
+ Sc
+ At

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Last updated: 15 Jul 2024