Interactor 1: ORC5 (Q24169)
Origin recognition complex subunit 5
Gene: ORC5

Interactor 2: Q7K2L1 (Q7K2L1)
Origin recognition complex subunit 3
Gene: Orc3

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 27016737, 29899147, 25762138, 32848132
Identification Methods affinity chromatography technology, pull down, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_16~ORC3_N, ORC3_N~ORC5_C, ORC5_C~ORC_WH_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005664 - nuclear origin of replication recognition complex
GO:0006260 - DNA replication
GO:0006270 - DNA replication initiation
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 460
Dm

1 721
+ Hs
+ Dm
+ Dm
+ Dm
+ At
+ Hs
+ Hs
+ Hs
+ At
+ Sp
+ At
+ Sp
+ Sp
+ Sp

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Last updated: 15 Jul 2024