HitPredict

Interactor 1: DIAP1 (Q24306)
Death-associated inhibitor of apoptosis 1 (EC 2.3.2.27) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread) (RING-type E3 ubiquitin transferase Diap1)
Gene: DIAP1

Interactor 2: DRONC (Q9XYF4)
Caspase Dronc (EC 3.4.22.-) (NEDD2-like caspase) [Cleaved into: Caspase Nc subunit 1; Caspase Nc subunit 2]
Gene: DRONC

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 21343367, 10675329, 15774476, 25146930, 16322754, 18084239, 15107838, 15710747, 14517550, 12021771, 20700104, unassigned4
Identification Methods affinity chromatography technology, two hybrid, pull down, enzymatic study, molecular sieving, tandem affinity purification, anti tag coimmunoprecipitation, coimmunoprecipitation, two hybrid fragment pooling approach, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BIR~Peptidase_C14
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0022416 - chaeta development
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 438
Dm

1 450
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Last updated: 15 Jul 2024