Interactor 1: DIAP2 (Q24307)
Death-associated inhibitor of apoptosis 2 (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2)
Gene: DIAP2

Interactor 2: CASP8 (Q8IRY7)
Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
Gene: Dredd

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 25968339, 22549468, 21730059
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BIR~Peptidase_C14
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0006964 - positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
GO:0045087 - innate immune response
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 498
Dm

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Last updated: 15 Jul 2024