Interactor 1: ESC (Q24338)
Polycomb protein esc (Protein extra sex combs)
Gene: ESC

Interactor 2: SUZ12 (Q9NJG9)
Polycomb protein Su(z)12 (Suppressor 12 of zeste protein)
Gene: Su(z)12

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 12697833, 12408864, 24100017, 26063573, 29242288, 29070704, 25242320, 15896722, 15776017, 16537908
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains VEFS-Box~WD40
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0035097 - histone methyltransferase complex
GO:0035098 - ESC/E(Z) complex
GO:0140718 - facultative heterochromatin formation
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 425
Dm

1 900
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ At
+ At

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Last updated: 15 Jul 2024