HitPredict

Interactor 1: DICH (Q24533)
SOX domain-containing protein dichaete (Protein fish-hook)
Gene: D

Interactor 2: DICH (Q24533)
SOX domain-containing protein dichaete (Protein fish-hook)
Gene: D

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.884

The method score is based on:

Property Details
Experiments 10844029, 37061542, unassigned2874, unassigned4
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, experimental interaction detection
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~HMG_box
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002168 - instar larval development
and 24 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 382
Dm

1 382
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024