HitPredict

Interactor 1: ERC6L (Q2NKX8)
DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) (PLK1-interacting checkpoint helicase) (Tumor antigen BJ-HCC-15)
Gene: ERCC6L

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1250 Hs			1 126
+	Hs
		229415 SMCA5_HUMAN (16-1037): 0: 635: 21.42		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		229458 SMCA5_HUMAN (16-1037): 0: 635: 21.42		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		229321 SMCA5_HUMAN (16-1037): 0: 635: 21.42		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		229353 SMCA5_HUMAN (16-1037): 0: 635: 21.42		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		658684 SMCA1_HUMAN (16-1020): 0: 627: 21.58		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		658646 SMCA1_HUMAN (16-1020): 0: 627: 21.58		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		1018625 CHD3_HUMAN (21-1080): 0: 610: 18.53		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		241591 CHD5_HUMAN (14-1000): 0: 611: 17.83		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		918541 CHD5_HUMAN (14-1000): 0: 611: 17.83		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		241517 CHD3_HUMAN (21-1080): 0: 610: 18.53		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		707612 CHD3_HUMAN (21-1080): 0: 610: 18.53		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918325 CHD3_HUMAN (21-1080): 0: 610: 18.53		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		151395 CHD1_HUMAN (30-1070): 0: 608: 19.62		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		846990 SMCA4_HUMAN (14-896): 0: 605: 21.05		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		846915 SMCA4_HUMAN (14-896): 0: 605: 21.05		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		707773 CHD7_HUMAN (40-756): 2.23e-180: 593: 24.43		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918744 CHD7_HUMAN (40-756): 2.23e-180: 593: 24.43		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Sc
		355836 CHD1_YEAST (1-1172): 0: 611: 19.62		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sp
		144534 HRP3_SCHPO (40-1037): 0: 594: 19.54		H2B1_SCHPO (4-125): 6.05e-46: 146: 70.49
+	Sc
		355410 CHD1_YEAST (1-1172): 0: 611: 19.62		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13