HitPredict

Interactor 1: ERC6L (Q2NKX8)
DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) (PLK1-interacting checkpoint helicase) (Tumor antigen BJ-HCC-15)
Gene: ERCC6L

Interactor 2: WDFY2 (Q96P53)
WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2) (Zinc finger FYVE domain-containing protein 22)
Gene: WDFY2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1250 Hs			1 400
+	Dm
		631309 BRM_DROME (14-997): 0: 582: 20.30		EBI_DROME (2-274): 2.4e-66: 225: 12.72
+	Hs
		903234 CHD4_HUMAN (24-992): 0: 588: 18.51		WDR5_HUMAN (103-398): 1.77e-65: 213: 15.00
+	Hs
		658715 SMCA1_HUMAN (16-1020): 0: 627: 21.58		SNR40_HUMAN (1-94): 1.32e-16: 82.5: 11.88
+	Hs
		1018633 CHD3_HUMAN (21-1080): 0: 610: 18.53		SNR40_HUMAN (1-94): 1.32e-16: 82.5: 11.88
+	Hs
		151443 CHD1_HUMAN (30-1070): 0: 608: 19.62		SNR40_HUMAN (1-94): 1.32e-16: 82.5: 11.88
+	Sc
		697383 CHD1_YEAST (1-1172): 0: 611: 19.62		TAF5_YEAST (148-272): 7.02e-15: 78.7: 21.68
+	Hs
		847053 SMCA4_HUMAN (14-896): 0: 605: 21.05		SNR40_HUMAN (1-94): 1.32e-16: 82.5: 11.88
+	Hs
		1018493 CHD3_HUMAN (21-1080): 0: 610: 18.53		PWP2_HUMAN (19-275): 3.43e-10: 64: 14.75
+	Hs
		1018714 CHD3_HUMAN (21-1080): 0: 610: 18.53		NLE1_HUMAN (343-399): 3.76e-09: 60.1: 14.04
+	Hs
		1059627 CHD4_HUMAN (24-992): 0: 588: 18.51		PWP2_HUMAN (19-275): 3.43e-10: 64: 14.75
+	Sc
		687689 BTAF1_YEAST (96-628): 6.48e-56: 216: 31.32		TAF5_YEAST (148-272): 7.02e-15: 78.7: 21.68