Interactor 1: GSK3A (Q2NL51)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Interactor 2: ACVL1 (Q61288)
Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: Acvrl1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24319055
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase, Pkinase~TGF_beta_GS
Common GO terms GO:0005524 - ATP binding
GO:0019901 - protein kinase binding
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 490
Mm

1 502
+ Mm
+ At
+ At
+ At
+ At
+ At
+ Dm
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024