HitPredict

Interactor 1: SGK1 (Q2PJ68)
Serine/threonine-protein kinase sgk-1 (EC 2.7.11.1) (Serum- and glucocorticoid-inducible kinase homolog) (Serum/glucocorticoid-regulated kinase 1)
Gene: sgk-1

Interactor 2: PDPK1 (Q9Y1J3)
3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (Pdk-class protein kinase 1)
Gene: pdk-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 15068796, 21348927
Identification Methods affinity chromatography technology, enzymatic study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 3 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 463
Ce

1 636
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024