HitPredict

Interactor 1: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Interactor 2: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29298432
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016607 - nuclear speck GO:0071011 - precatalytic spliceosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 953
+	Hs
		903347 WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1201588 SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1056988 WDR26_HUMAN (3-513): 2.59e-99: 314: 19.45		MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73
+	Hs
		793042 LIS1_HUMAN (4-472): 9.67e-90: 282: 15.13		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		929542 RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1016295 TBL3_HUMAN (213-376): 4.84e-09: 60.8: 24.55		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Rn
		870010 GBB2_RAT (300-512): 1.32e-46: 167: 18.31		FNDC1_RAT (146-941): 7.74e-45: 178: 10.27
+	Mm
		903669 WDR5_MOUSE (78-425): 2.83e-76: 245: 21.25		KMT2C_MOUSE (260-934): 3.18e-12: 73.1: 17.15
+	Hs
		152622 WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25		KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30
+	Hs
		1302927 NLE1_HUMAN (433-513): 1.02e-23: 106: 23.46		MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24
+	Hs
		1288258 SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50		MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24
+	Hs
		1346970 NLE1_HUMAN (433-513): 1.02e-23: 106: 23.46		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		1288394 SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		1222858 NLE1_HUMAN (433-513): 1.02e-23: 106: 23.46		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		1222821 SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		1264784 SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50		TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54
+	Hs
		1056932 SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50		MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73
+	Hs
		152663 WDR5B_HUMAN (428-512): 2.8e-18: 87.7: 22.35		KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30
+	Hs
		929460 RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33		MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73