HitPredict

Interactor 1: CKB12 (Q2V419)
Cyclin-dependent kinase B1-2 (CDKB1;2) (EC 2.7.11.22) (EC 2.7.11.23)
Gene: CDKB1-2

Interactor 2: CCA34 (Q3ECW2)
Cyclin-A3-4 (G2/mitotic-specific cyclin-A3-4) (CycA3;4)
Gene: CYCA3-4

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20407024
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 311 At			1 370
+	At
		1103369 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA31_ARATH (3-366): 1.67e-119: 351: 66.03
+	At
		1103349 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA23_ARATH (6-361): 7.64e-107: 322: 40.78
+	At
		1059417 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA22_ARATH (1-362): 2.56e-106: 320: 42.27
+	At
		1103352 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA21_ARATH (1-362): 5.36e-105: 317: 39.78
+	At
		1103366 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA24_ARATH (51-361): 3.18e-104: 316: 46.62
+	Hs
		625350 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNA1_HUMAN (15-359): 3.17e-101: 308: 35.84
+	Hs
		538471 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNB1_HUMAN (39-365): 1.05e-98: 301: 32.83
+	Hs
		303829 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNB2_HUMAN (4-365): 1.88e-98: 299: 28.88
+	Hs
		590125 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNA2_HUMAN (1-358): 2.23e-97: 297: 33.61
+	At
		639335 CKB11_ARATH (1-311): 3.89e-139: 397: 87.78		CCA22_ARATH (1-362): 2.56e-106: 320: 42.27
+	At
		1103350 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCB12_ARATH (3-358): 1.78e-96: 295: 29.12
+	At
		1103371 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCB23_ARATH (2-356): 1.43e-95: 293: 27.84
+	Hs
		538521 CDK3_HUMAN (1-309): 9.3e-142: 403: 56.77		CCNB1_HUMAN (39-365): 1.05e-98: 301: 32.83
+	Mm
		956329 CDK2_MOUSE (1-309): 2.79e-140: 401: 49.16		CCNA1_MOUSE (15-359): 1.66e-99: 302: 36.13
+	Hs
		590162 CDK3_HUMAN (1-309): 9.3e-142: 403: 56.77		CCNA2_HUMAN (1-358): 2.23e-97: 297: 33.61
+	Mm
		851183 CDK2_MOUSE (1-309): 2.79e-140: 401: 49.16		CCNA2_MOUSE (1-358): 7.33e-98: 298: 34.71
+	At
		672516 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCB11_ARATH (4-358): 6.06e-89: 276: 27.70
+	At
		1103376 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCB31_ARATH (7-358): 2.59e-86: 268: 26.42
+	At
		639330 CKB11_ARATH (1-311): 3.89e-139: 397: 87.78		CCB11_ARATH (4-358): 6.06e-89: 276: 27.70
+	At
		1103351 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCB22_ARATH (117-349): 8.96e-38: 142: 39.91