HitPredict

Interactor 1: TR16L (Q309B1)
Tripartite motif-containing protein 16-like protein (Tripartite motif-containing protein 70)
Gene: TRIM16L

Interactor 2: NLRP1 (Q9C000)
NACHT, LRR and PYD domains-containing protein 1 (EC 3.4.-.-) (EC 3.6.4.-) (Caspase recruitment domain-containing protein 7) (Death effector filament-forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus (NLRP1-CT); NACHT, LRR and PYD domains-containing protein 1, N-terminus (NLRP1-NT)]
Gene: NLRP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16575408
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 348 Hs			1 1473
+	Hs
		1149907 TRI68_HUMAN (4-335): 1.73e-97: 298: 17.16		NLRP1_HUMAN (1-1473): 0: 1530: 100.00
+	Hs
		183335 MEFV_HUMAN (3-337): 1.26e-88: 284: 18.83		NLRP1_HUMAN (1-1473): 0: 1530: 100.00
+	Hs
		1052765 TRI25_HUMAN (2-333): 1.18e-68: 228: 20.46		NLRP1_HUMAN (1-1473): 0: 1530: 100.00
+	Hs
		1162057 TRI65_HUMAN (2-341): 1.16e-48: 172: 19.36		NLRP1_HUMAN (1-1473): 0: 1530: 100.00
+	Mm
		1112452 Q3UCL2_MOUSE (3-333): 4.61e-108: 325: 16.34		NLRP3_MOUSE (199-1105): 0: 646: 30.52
+	Hs
		183332 MEFV_HUMAN (3-337): 1.26e-88: 284: 18.83		NLRP3_HUMAN (199-1102): 0: 634: 31.19
+	Mm
		1207564 TRI47_MOUSE (3-334): 5.19e-82: 263: 21.41		NLRP3_MOUSE (199-1105): 0: 646: 30.52
+	Mm
		1194997 TRI50_MOUSE (3-345): 2.96e-76: 244: 16.14		NLRP3_MOUSE (199-1105): 0: 646: 30.52
+	Mm
		1207374 TRI14_MOUSE (19-331): 3.23e-74: 237: 23.10		NLRP3_MOUSE (199-1105): 0: 646: 30.52
+	Mm
		1206333 TRI65_MOUSE (2-342): 6.64e-68: 223: 22.52		NLRP3_MOUSE (199-1105): 0: 646: 30.52
+	Hs
		183339 MEFV_HUMAN (3-337): 1.26e-88: 284: 18.83		NALP2_HUMAN (142-1098): 2.1e-176: 557: 25.34
+	Hs
		1162050 TRI65_HUMAN (2-341): 1.16e-48: 172: 19.36		NLRP3_HUMAN (199-1102): 0: 634: 31.19
+	Hs
		135016 TRI38_HUMAN (3-334): 5.13e-89: 276: 14.37		NLRP6_HUMAN (221-981): 8.85e-134: 437: 29.64
+	Hs
		702498 TRI22_HUMAN (3-334): 2.59e-83: 263: 15.68		C2TA_HUMAN (118-1008): 1.14e-120: 408: 20.96
+	Hs
		183340 MEFV_HUMAN (3-337): 1.26e-88: 284: 18.83		ASC_HUMAN (1353-1459): 1.19e-42: 156: 50.00
+	Hs
		537077 TRI27_HUMAN (1-334): 1.88e-101: 310: 19.54		NOD2_HUMAN (898-1136): 4.02e-13: 76.7: 14.80
+	Hs
		1223391 TRI22_HUMAN (3-334): 2.59e-83: 263: 15.68		NOD2_HUMAN (898-1136): 4.02e-13: 76.7: 14.80
+	Hs
		1261111 TRI41_HUMAN (3-331): 1.7e-79: 256: 19.28		NOD2_HUMAN (898-1136): 4.02e-13: 76.7: 14.80
+	Hs
		527988 TRI14_HUMAN (19-331): 4.5e-68: 221: 22.80		RINI_HUMAN (676-928): 1.87e-19: 95.2: 22.22
+	Hs
		886400 TRI25_HUMAN (2-333): 1.18e-68: 228: 20.46		NAL12_HUMAN (917-1185): 4.71e-10: 66.7: 15.49