HitPredict

Interactor 1: Q32KD4 (Q32KD4)
Argonaute-1, isoform A (Argonaute-1, isoform C) (Argonaute-1, isoform D) (LP02696p) (SD07283p)
Gene: AGO1

Interactor 2: BRAT (Q8MQJ9)
Brain tumor protein
Gene: BRAT

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	18528333, 29354790
Identification Methods	affinity chromatography technology, protein complementation assay, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0017148 - negative regulation of translation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 984 Dm			1 1037
+	Dm
		1100037 Q27IR0_DROME (109-938): 0: 1154: 100.00		BRAT_DROME (1-1037): 0: 799: 100.00
+	Dm
		1103832 Q32KD4_DROME (1-984): 0: 1333: 100.00		WECH_DROME (275-1018): 4.02e-89: 306: 16.67
+	Hs
		170510 AGO1_HUMAN (125-984): 0: 1158: 73.64		TIF1A_HUMAN (159-783): 6.88e-90: 312: 12.96
+	Hs
		170508 AGO2_HUMAN (133-984): 0: 1152: 74.21		TIF1A_HUMAN (159-783): 6.88e-90: 312: 12.96
+	Dm
		1100038 Q27IR0_DROME (109-938): 0: 1154: 100.00		WECH_DROME (275-1018): 4.02e-89: 306: 16.67
+	Hs
		170478 AGO3_HUMAN (125-984): 0: 1137: 71.61		TIF1A_HUMAN (159-783): 6.88e-90: 312: 12.96
+	Mm
		1093411 AGO2_MOUSE (113-984): 0: 1157: 73.00		LIN41_MOUSE (169-1027): 5.62e-81: 283: 14.26
+	Hs
		170484 AGO4_HUMAN (122-984): 0: 1119: 70.66		TIF1A_HUMAN (159-783): 6.88e-90: 312: 12.96
+	Ce
		108593 G5EGR6_CAEEL (10-984): 0: 1115: 62.32		LIN41_CAEEL (67-1027): 3.05e-88: 309: 15.30
+	Dm
		1103862 Q32KD4_DROME (1-984): 0: 1333: 100.00		Q9W378_DROME (642-1028): 4.92e-16: 85.5: 15.54
+	Hs
		164503 AGO2_HUMAN (133-984): 0: 1152: 74.21		TRI66_HUMAN (161-713): 4.36e-63: 236: 11.27
+	Mm
		1208468 AGO1_MOUSE (125-984): 0: 1158: 73.64		TRI32_MOUSE (235-900): 5.76e-63: 228: 13.20
+	Hs
		1317538 AGO2_HUMAN (133-984): 0: 1152: 74.21		TRI55_HUMAN (179-779): 3.27e-58: 212: 12.32
+	Hs
		1282069 AGO2_HUMAN (133-984): 0: 1152: 74.21		TRI63_HUMAN (310-531): 1.72e-51: 187: 18.34
+	Hs
		1102507 AGO2_HUMAN (133-984): 0: 1152: 74.21		LIN41_HUMAN (781-1026): 1.17e-28: 125: 22.76
+	Dm
		1100039 Q27IR0_DROME (109-938): 0: 1154: 100.00		Q9W378_DROME (642-1028): 4.92e-16: 85.5: 15.54
+	Hs
		1294945 PIWL1_HUMAN (56-951): 0: 766: 20.89		TRI54_HUMAN (313-565): 9.07e-39: 150: 16.54
+	Ce
		998324 YQ53_CAEEL (371-939): 1.73e-36: 151: 25.08		Q19818_CAEEL (131-1037): 6.83e-125: 408: 16.57
+	Ce
		247863 ERGO1_CAEEL (413-942): 1.47e-51: 199: 27.65		LIN41_CAEEL (67-1027): 3.05e-88: 309: 15.30