HitPredict

Interactor 1: EMAL3 (Q32P44)
Echinoderm microtubule-associated protein-like 3 (EMAP-3)
Gene: EML3

Interactor 2: NEK7 (Q8TDX7)
Serine/threonine-protein kinase Nek7 (EC 2.7.11.34) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)
Gene: NEK7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 302
+	Hs
		1104147 EMAL3_HUMAN (1-896): 0: 558: 100.00		NEK6_HUMAN (12-302): 1.58e-139: 397: 81.44
+	Hs
		1104140 EMAL3_HUMAN (1-896): 0: 558: 100.00		NEK1_HUMAN (38-295): 4.6e-53: 188: 38.31
+	Hs
		1104134 EMAL3_HUMAN (1-896): 0: 558: 100.00		NEK9_HUMAN (40-290): 1.05e-48: 175: 39.29
+	Hs
		254137 WDR1_HUMAN (262-624): 1.44e-44: 172: 10.49		AKT3_HUMAN (2-294): 6.75e-126: 369: 23.43
+	Hs
		325574 EMAL2_HUMAN (587-896): 6.05e-26: 116: 13.62		NEK6_HUMAN (12-302): 1.58e-139: 397: 81.44
+	Hs
		1335710 EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51		NEK6_HUMAN (12-302): 1.58e-139: 397: 81.44
+	Hs
		1255597 EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51		NEK7_HUMAN (1-302): 1.91e-124: 359: 100.00
+	Dm
		1213409 NLE_DROME (151-252): 4.56e-11: 68.1: 13.46		AKT1_DROME (23-294): 2.43e-122: 364: 24.55
+	Hs
		1254380 EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51		NEK9_HUMAN (40-290): 1.05e-48: 175: 39.29
+	Hs
		851739 PRP19_HUMAN (361-664): 3.33e-12: 71.8: 15.71		NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23
+	Hs
		127925 EMAL1_HUMAN (760-894): 5.57e-09: 61.9: 8.11		NEK9_HUMAN (40-290): 1.05e-48: 175: 39.29