Interactor 1: ORC1 (Q13415)
Origin recognition complex subunit 1 (Replication control protein 1)
Gene: ORC1
Interactor 2: DOT1L (Q8TEK3)
Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)
Gene: DOT1L
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.55 | 0.513 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000781 - chromosome, telomeric region GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
