HitPredict

Interactor 1: RAC5 (Q38937)
Rac-like GTP-binding protein ARAC5 (AtRAC5) (GTPase protein ROP4)
Gene: ARAC5

Interactor 2: SPK1 (Q8SAB7)
Guanine nucleotide exchange factor SPIKE 1
Gene: SPK1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	18308939
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	DHR-2_Lobe_B~Ras, DHR-2_Lobe_C~Ras
Common GO terms	GO:0005634 - nucleus GO:0007264 - small GTPase-mediated signal transduction GO:0008360 - regulation of cell shape
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 At			1 1830
+	At
		287603 RAC10_ARATH (2-180): 5.17e-81: 241: 82.12		SPK1_ARATH (1-1830): 0: 2088: 100.00
+	At
		1248269 RAC9_ARATH (7-196): 9.25e-77: 230: 76.96		SPK1_ARATH (1-1830): 0: 2088: 100.00
+	At
		1105105 RAC1_ARATH (1-196): 1.3e-76: 229: 87.82		SPK1_ARATH (1-1830): 0: 2088: 100.00
+	Hs
		892410 RAC3_HUMAN (7-178): 5.29e-91: 266: 64.37		DOC11_HUMAN (77-1827): 0: 1614: 21.33
+	Hs
		925332 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOC11_HUMAN (77-1827): 0: 1614: 21.33
+	Hs
		545421 RAC2_HUMAN (7-196): 1.1e-75: 227: 61.46		DOC11_HUMAN (77-1827): 0: 1614: 21.33
+	Hs
		892573 RAC3_HUMAN (7-178): 5.29e-91: 266: 64.37		DOCK9_HUMAN (46-1827): 0: 1537: 19.31
+	Hs
		925588 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK9_HUMAN (46-1827): 0: 1537: 19.31
+	Hs
		925518 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK6_HUMAN (16-979): 0: 755: 20.07
+	Hs
		925526 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK7_HUMAN (14-731): 0: 656: 21.52
+	Hs
		925448 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK8_HUMAN (14-731): 0: 602: 20.24
+	Hs
		925429 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK4_HUMAN (463-1026): 7.18e-139: 479: 16.22
+	Dm
		776892 RAC1_DROME (7-196): 6.43e-77: 230: 60.42		Q8MQW7_DROME (1270-1830): 2.47e-131: 446: 15.17
+	Hs
		925425 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK3_HUMAN (463-1026): 4.99e-70: 264: 15.18
+	Mm
		925807 RAC1_MOUSE (7-196): 2.18e-79: 236: 62.50		DOCK1_MOUSE (463-1017): 1.06e-47: 190: 15.15
+	Hs
		925620 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK5_HUMAN (463-1026): 4.43e-47: 188: 14.88
+	Hs
		925276 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK1_HUMAN (463-1017): 1.06e-45: 184: 14.96
+	Hs
		925486 RAC1_HUMAN (7-196): 2.18e-79: 236: 62.50		DOCK2_HUMAN (463-1026): 1.04e-43: 177: 13.46
+	Hs
		545372 RAC2_HUMAN (7-196): 1.1e-75: 227: 61.46		DOCK1_HUMAN (463-1017): 1.06e-45: 184: 14.96
+	Hs
		545535 RAC2_HUMAN (7-196): 1.1e-75: 227: 61.46		DOCK2_HUMAN (463-1026): 1.04e-43: 177: 13.46