Interactor 1: TOP3A (Q13472)
DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha)
Gene: TOP3A
Interactor 2: SPIDR (Q14159)
DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair)
Gene: SPIDR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.51 | 0.55 | 0.530 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23509288 |
| Identification Methods | affinity chromatography technology, pull down, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000724 - double-strand break repair via homologous recombination GO:0005654 - nucleoplasm |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
