HitPredict

Interactor 1: H7BXF5 (H7BXF5)
Sin3A associated protein 130
Gene: SAP130

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0070822 - Sin3-type complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1056 Hs			1 482
+	Hs
		1038696 SP130_HUMAN (1-1056): 1.22e-109: 367: 96.41		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1270429 SP130_HUMAN (1-1056): 1.22e-109: 367: 96.41		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1038645 CIC_HUMAN (1-542): 2.24e-12: 73.9: 9.41		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1270390 CIC_HUMAN (1-542): 2.24e-12: 73.9: 9.41		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		152639 KMT2D_HUMAN (214-899): 1.07e-09: 65.1: 8.89		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		203227 SYNJ1_HUMAN (256-707): 2.53e-09: 63.9: 10.62		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		177326 ANR11_HUMAN (98-1019): 1.21e-31: 137: 12.64		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		1056969 MDC1_HUMAN (80-956): 1.04e-23: 110: 9.85		HDAC8_HUMAN (32-371): 2.54e-139: 407: 43.11