HitPredict

Interactor 1: H7BYY1 (H7BYY1)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0015629 - actin cytoskeleton
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 457
+	Hs
		451318 TPM1_HUMAN (6-248): 1.34e-49: 165: 70.78		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		932058 TPM4_HUMAN (1-248): 5.54e-49: 163: 77.82		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		419055 TPM3_HUMAN (6-248): 5.4e-48: 161: 65.43		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		434438 TPM2_HUMAN (5-248): 6.66e-43: 148: 63.53		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Mm
		886037 TPM1_MOUSE (6-248): 1.22e-49: 165: 70.37		PDLI5_MOUSE (1-282): 2.11e-28: 120: 24.47
+	Mm
		886046 TPM2_MOUSE (5-248): 4.88e-43: 148: 63.53		PDLI5_MOUSE (1-282): 2.11e-28: 120: 24.47
+	Hs
		434422 TPM2_HUMAN (5-248): 6.66e-43: 148: 63.53		PDLI5_HUMAN (1-282): 6.17e-28: 118: 24.82
+	Hs
		434336 TPM2_HUMAN (5-248): 6.66e-43: 148: 63.53		ZN250_HUMAN (362-457): 4.28e-23: 103: 6.25
+	Hs
		932007 TPM4_HUMAN (1-248): 5.54e-49: 163: 77.82		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		418964 TPM3_HUMAN (6-248): 5.4e-48: 161: 65.43		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		1076422 Q5VU62_HUMAN (91-248): 4.07e-44: 147: 67.09		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42